Obstet Gynecol Sci.  2023 Nov;66(6):498-508. 10.5468/ogs.23114.

Clinical relevance of sentinel lymph node biopsy in early ovarian cancer

• Seon KE
• Kim SW
• Kim YT

• KMID: 2547851
• DOI: http://doi.org/10.5468/ogs.23114

Abstract

The first-line treatment for early ovarian cancer typically involves primary debulking surgery aimed at maximal cytoreduction, alongside adjuvant chemotherapy if clinically indicated. Nodal assessment involving pelvic and para-aortic lymph node dissection is typically performed during the primary debulking surgery. However, the survival benefit of lymphadenectomy in patients with early ovarian cancer has not been well established, and the procedure is associated with longer operation time and higher perioperative complications. With the emergence of minimally invasive surgery as a potential alternative to laparotomy for early ovarian cancer, sentinel lymph node biopsy has been evaluated in this setting. In this review, we summarized the current literature regarding sentinel lymph node biopsy in patients with early ovarian cancer, focusing on the clinical relevance of this method, including its detection rate and diagnostic accuracy. Additionally, we discuss the current status of clinical trials investigating sentinel lymph node biopsy in early ovarian cancer cases.

Keyword

Ovarian cancer; Sentinel lymph node biopsy; Operative surgical procedure

Figure

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  Fig. 1 Single-port assisted laparoscopic indocyanine green (ICG) injection at infundibulo-pelvic (IP) ligament stump. (A) ICG tracer injection at right IP ligament stump; (B) sentinel lymph node identification. Rt, right; L3M, inframesenteric aortocaval; L4M, supramesenteric aortocaval area.

Reference

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