Ann Pediatr Endocrinol Metab.  2023 Sep;28(3):159-167. 10.6065/apem.2346096.048.

Hypoparathyroidism in children and adolescents

• Korkmaz HA
• Ozkan B

• KMID: 2546339
• DOI: http://doi.org/10.6065/apem.2346096.048

Abstract

Hypoparathyroidism is characterized by insufficient parathyroid hormone (PTH) release from the parathyroid glands to maintain serum calcium level within normal limits and unresponsiveness of target tissues despite normal serum PTH level. Hypoparathyroidism is defined as low or inappropriately normal serum PTH level. In this narrative review, we discuss the etiology of hypoparathyroidism in children.

Keyword

Calcium; Hypocalcemia; Child; Parathyroid hormone; Hypoparathyroidism

Figure

• 

  Fig. 1. Investigating the etiology of hypocalcemia in children. PTH, parathyroid hormone; HRD, hypoparathyroidism, retardation, dysmorphism; CaSR, calcium-sensing receptor; OD, autosomal-dominant; HDR, hypoparathyroidism, deafness, renal dysplasia; MELAS, mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes; PTHR1, parathyroid hormone receptor 1.

Reference

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