J Yeungnam Med Sci.  2023 Jul;40(3):308-310. 10.12701/jyms.2022.00675.

Morgagni-Stewart-Morel syndrome presenting with neurological symptoms: a case report

• Tosunoğlu B
• Ergin N
• Kaya N
• Ertuğrul İnan L

• KMID: 2544594
• DOI: http://doi.org/10.12701/jyms.2022.00675

Abstract

Morgagni-Stewart-Morel (MSM) syndrome is characterized by the thickening of the frontal bone of the skull (hyperostosis frontalis interna) obesity, neurological symptoms, and hypertrichosis. We present the case of a 76-year-old patient who complained of confusion, extreme irritability, and headache and was diagnosed with MSM based on examination, imaging, and test results.

Keyword

Endocrine; Hirsutism; Hyperostosis frontalis; Hyperparathyroidism

Figure

• 

  Fig. 1. Axial brain computed tomography scan shows bilateral overgrowth of the inner table of the frontal bone.

• 

  Fig. 2. Sagittal T1-weighted magnetic resonance imaging cranial scan shows nodular bony overgrowth involving the frontal endocranium and moderate cortical atrophy.

Reference

References

1. Attanasio F, Granziera S, Giantin V, Manzato E. Full penetrance of Morgagni-Stewart-Morel syndrome in a 75-year-old woman: case report and review of the literature. J Clin Endocrinol Metab. 2013; 98:453–7.

2. Abainou L, El Jadi H, El Hadri S, Baizri H. Morgagni-Stewart-Morel syndrome: a new case. Case Rep Int. 2019; 8:100070Z06LA2019.

3. Doğan E, Mouline M. Morgagni-Stewart-Morel syndrome: case report. Turk J Clin Lab. 2019; 10:434–6.

4. Nallegowda M, Singh U, Khanna M, Yadav SL, Choudhary AR, Thakar A. Morgagni Stewart Morel syndrome--additional features. Neurol India. 2005; 53:117–9.

5. Kishore B, Singh MM, Seth HC, Hazra DK, Trehon OP, Prakash C. Morgagni’s syndrome: a case report. J Indian Med Assoc. 1972; 58:376–8.