Cardiovasc Imaging Asia.  2023 Jan;7(1):6-9. 10.22468/cvia.2022.00157.

Non-Hodgkin’s Lymphoma Presenting as Intracardiac Mass: A Rare Presentation

Affiliations
  • 1Department of Cardiology, Sarawak Heart Center, Kota Samarahan, Sarawak, Malaysia
  • 2Department of Medicine, Faculty of Medicine and Health Sciences, University of Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia
  • 3Haematology Unit, Department of Medicine, Sarawak General Hospital, Kuching, Sarawak, Malaysia

Abstract

Primary cardiac lymphoma (PCL) comprises of 1%–2% of primary cardiac tumors. This case report describes a rare case of PCL with rapid disease progression. A 51-year-old female presented with 6 months of dyspnea. Her transthoracic echocardiogram showed a large exudative circumferential pericardial effusion and bi-atrial masses. An endovascular tissue biopsy using intra-cardiac echocardiography guidance enabled the diagnosis of diffuse large B-cell lymphoma. Staging computed tomography staged the disease at Ann Arbor stage IV E. She achieved a complete response to rituximab, cyclophosphamide, hydroxydaunorubicin, vincristine, and prednisolone chemoimmunotherapy.

Keyword

Non-Hodgkin lymphoma; Diffuse large B-cell lymphoma; Primary cardiac lymphoma; Intra-cardiac echocardiography
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