J Chest Surg.  2023 May;56(3):220-223. 10.5090/jcs.22.107.

Well-Differentiated Papillary Mesothelial Tumor: An Unusual Radiologic Presentation: A Case Report

Affiliations
  • 1Departments of Cardiothoracic Surgery, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK
  • 2Departments of Radiology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK
  • 3Departments of Cellular Pathology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK
  • 4Departments of Radiology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK
  • 5MESOPATH College, Unit of Cancer Research Center INSERM U1052-Centre Léon Bérard, Lyon, France
  • 6Department of Cardiothoracic Surgery, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK

Abstract

Well-differentiated papillary mesothelial tumor (WDPMT) is an uncommon tumor, formerly named well-differentiated papillary mesothelioma in the 2015 World Health Organization classification. It has a characteristic papillary architecture, bland cytologic features, a tendency toward superficial spread without invasion, and a good prognosis due to its clinically indolent behavior with prolonged survival. Rare cases with superficial invasion are termed WDPMT with invasive foci. WDPMT occurs primarily in the peritoneum of reproductive-age women, but also rarely in the pleura. We report a case of a 60-year-old woman who developed WDPMT with minimal invasion in the pleura with atypical radiological features and a family history of mesothelioma and indirect asbestos exposure.

Keyword

Well-differentiated papillary mesothelial tumor; Stromal invasion; Pleura; Case report
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