Korean J Blood Transfus.
2023 Apr;34(1):21-25. 10.17945/kjbt.2023.34.1.2 1.
Effectiveness of Malaria Antibody Test for Screening Blood Donors
- Affiliations
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- 1Blood Transfusion Research Institute, Korean Red Cross, Wonju, Korea
- 2Nambu Blood Laboratory Center, Korean Red Cross, Busan, Korea
- KMID: 2541996
- DOI: http://doi.org/10.17945/kjbt.2023.34.1.2 1
Abstract
- The Republic of Korea has been using malaria antibody assays to screen blood donors and reduce the risk of transfusion-transmitted malaria (TTM). This study examined the effectiveness of the current malaria antibody test for screening blood donors and calculated the positive predictive value (PPV) with the real-time polymerase chain reaction (RT-PCR) as the reference. The reactive rate and PPV of the malaria antibody screening assay during particular period from 2020 to 2021 were 0.82% (248/30,309) and 0.40% (1/248), respectively. The low PPV of current malaria antibody screening in blood donors suggests that the effectiveness of this test is limited in terms of balancing blood safety and supply in low-prevalence situations.
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