Ann Clin Nutr Metab.  2023 Apr;15(1):2-7. 10.15747/ACNM.2023.15.1.2.

Efficacy of monounsaturated fatty acids in reducing risk of the cardiovascular diseases, cancer, inflammation, and insulin resistance: a narrative review

• Kim KH
• Kim Y
• Seo KW

• KMID: 2541588
• DOI: http://doi.org/10.15747/ACNM.2023.15.1.2

Abstract

Purpose
The purpose of this review is to explore the potential benefits of monounsaturated fatty acids (MUFAs), specifically those found in olive oil, on weight loss, cardiovascular disease, cancer, inflammation, and insulin resistance. Additionally, this review examines the use of olive oil–based intravenous lipid emulsions (ILEs) in providing parenteral nutrition to patients with diverse needs.
Current concept
MUFAs, found in olive oil, nuts, and some animal foods, have been found to have numerous health benefits. A diet high in MUFAs can aid in weight loss and reduce the risk of cardiovascular disease. Olive oil, in particular, has been linked to a lower risk of cancer, inflammation, and insulin resistance. In addition, olive oil–based ILEs have been utilized for over two decades and are well tolerated by patients requiring parenteral nutrition.
Conclusion
A diet rich in MUFAs, specifically from olive oil, can provide numerous health benefits, including weight loss and reducing the risk of cardiovascular disease, cancer, inflammation, and insulin resistance. Additionally, olive oil–based ILEs have been shown to effectively provide nutrients to diverse populations requiring parenteral nutrition and have demonstrated the ability to preserve immune function and induce less lipid peroxidation than other ILEs. Further research is needed to fully understand the potential benefits of MUFAs and olive oil-based ILEs, but current evidence suggests that they may be a valuable addition to a healthy diet and medical treatment.

Keyword

Emulsions; Fat emulsions; intravenous; Olive oil; Parenteral nutrition