Int J Arrhythm.  2023 Mar;24(1):6. 10.1186/s42444-023-00089-z.

Cascade screening can be life‑saving: a family with multiple cases of brugada syndrome and sudden cardiac death

• Ghafouri P
• Taaghi S
• Keykhavani A
• Bozorgi A
• diz A

• KMID: 2541321
• DOI: http://doi.org/10.1186/s42444-023-00089-z

Abstract

Brugada syndrome (BrS) may cause a spectrum of symptoms from asymptomatic patients to those who experience cardiac arrest and sudden cardiac death. The diagnosis is confirmed after observation of type I Brugada pattern on the electrocardiogram. Following the diagnosis, risk stratification can help select therapeutic options. Cascade screening should be started to find other family members with BrS. We present a 41-year-old woman diagnosed with BrS, and cascade screening of her relatives unveiled a pedigree of BrS among their family.

Keyword

Brugada syndrome; Challenge test; Arrhythmia; Sodium channel blocker; Flecainide