Korean J Gastroenterol.  2023 Feb;81(2):100-103. 10.4166/kjg.2023.009.

Well-Differentiated Papillary Mesothelioma of the Peritoneum

• Ji JH
• Jung HI
• Park JJ

• KMID: 2539580
• DOI: http://doi.org/10.4166/kjg.2023.009

Figure

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  Fig. 1 Colonoscopic findings: Colonoscopy shows a 3 cm-sized submucosal lesion with hard consistency at the splenic flexure.

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  Fig. 2 Abdominopelvic CT findings: The abdominopelvic computed tomography shows a 3.0 cm-sized, smoothly outlined hypoattenuating, and slowly enhancing lesion at the splenic flexure of the colon.

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  Fig. 3 Surgical specimen of resected tumor: A beige-colored mass and omentum attached to it was resected. The cut section of the tumor showed a mixed pattern with whitish, yellowish, and brownish parenchyma.

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  Fig. 4 Histology findings of the surgically resected specimen: It shows a layer of cuboidal cells, minimal cytologic atypia, and no mitotic features. (H&E, ×1,000).

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  Fig. 5 Immunohistochemical staining of the surgical specimen: (A) Cytokeratin AE1/AE3 was positive (×400). (B) Calretinin was weak positive and diffuse (×400). (C) MOC-31 was negative (×400).

Reference

1. Butnor KJ, Sporn TA, Hammar SP, Roggli VL. 2001; Well-differentiated papillary mesothelioma. Am J Surg Pathol. 25:1304–1309. DOI: 10.1097/00000478-200110000-00012. PMID: 11688466.

2. Daya D, McCaughey WT. 1990; Well-differentiated papillary mesothelioma of the peritoneum. A clinicopathologic study of 22 cases. Cancer. 65:292–296. DOI: 10.1002/1097-0142(19900115)65:2<292::AID-CNCR2820650218>3.0.CO;2-W. PMID: 2295052.

3. Foyle A, Al-Jabi M, McCaughey WT. 1981; Papillary peritoneal tumors in women. Am J Surg Pathol. 5:241–249. DOI: 10.1097/00000478-198104000-00004. PMID: 7235119.

4. Goepel JR. 1981; Benign papillary mesothelioma of peritoneum: a histological, histochemical and ultrastructural study of six cases. Histopathology. 5:21–30. DOI: 10.1111/j.1365-2559.1981.tb01763.x. PMID: 7216174.

5. Lovell FA, Cranston PE. 1990; Well-differentiated papillary mesothelioma of the peritoneum. AJR Am J Roentgenol. 155:1245–1246. DOI: 10.2214/ajr.155.6.2122674. PMID: 2122674.

6. Goldblum J, Hart WR. 1995; Localized and diffuse mesotheliomas of the genital tract and peritoneum in women. A clinicopathologic study of nineteen true mesothelial neoplasms, other than adenomatoid tumors, multicystic mesotheliomas, and localized fibrous tumors. Am J Surg Pathol. 19:1124–1137. DOI: 10.1097/00000478-199510000-00003. PMID: 7573671.

7. Chen X, Sheng W, Wang J. 2013; Well-differentiated papillary mesothelioma: a clinicopathological and immunohistochemical study of 18 cases with additional observation. Histopathology. 62:805–813. DOI: 10.1111/his.12089. PMID: 23530588.

8. Hoekstra AV, Riben MW, Frumovitz M, Liu J, Ramirez PT. 2005; Well-differentiated papillary mesothelioma of the peritoneum: a pathological analysis and review of the literature. Gynecol Oncol. 98:161–167. DOI: 10.1016/j.ygyno.2005.03.031. PMID: 15894368.

9. Malpica A, Sant'Ambrogio S, Deavers MT, Silva EG. 2012; Well-differentiated papillary mesothelioma of the female peritoneum: a clinicopathologic study of 26 cases. Am J Surg Pathol. 36:117–127. DOI: 10.1097/PAS.0b013e3182354a79. PMID: 22024662.

10. Churg A, Allen T, Borczuk AC, et al. 2014; Well-differentiated papillary mesothelioma with invasive foci. Am J Surg Pathol. 38:990–998. DOI: 10.1097/PAS.0000000000000200. PMID: 24618613.

11. Lee YK, Jun HJ, Nahm JH, et al. 2013; Therapeutic strategies for well-differentiated papillary mesothelioma of the peritoneum. Jpn J Clin Oncol. 43:996–1003. DOI: 10.1093/jjco/hyt117. PMID: 23964112.

12. Ellis P, Davies AM, Evans WK, Haynes AE, Lloyd NS. Lung Cancer Disease Site Group of Cancer Care Ontariós Program in Evidencebased Care. 2006; The use of chemotherapy in patients with advanced malignant pleural mesothelioma: a systematic review and practice guideline. J Thorac Oncol. 1:591–60. DOI: 10.1016/S1556-0864(15)30366-X. PMID: 17409924.