J Korean Neurol Assoc.
2023 Feb;41(1):31-34. 10.17340/jkna.2023.1.4.
A Case of Inclusion Body Myositis with Clinical, Pathological and Serological Consideration
- Affiliations
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- 1Department of Neurology, Pusan National University School of Medicine, Busan, Korea
- 2Biomedical Research Institute, Pusan National University Hospital, Busan, Korea
- 3Department of Neurology, Kyoungpook National University Chilgok Hospital, Daegu, Korea
- 4Biomedical Research Institute, Pusan National University Yangsan Hospital, Busan, Korea
- KMID: 2539084
- DOI: http://doi.org/10.17340/jkna.2023.1.4
Abstract
- Inclusion body myositis is a rare condition of idiopathic inflammatory myopathy. Prior criteria for the diagnosis of inclusion body myositis essentially required pathological features of rimmed vacuoles, tubulofilamentous inclusions, and amyloid deposits. However, recently developed new diagnostic criteria emphasize clinical characteristics including weakness of finger flexors and knee extensors. In addition, a serological evaluation of anti-cN1A antibody is helpful for the diagnosis. We report a case of inclusion body myositis with clinical, pathological, and serological consideration.
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