Clin Endosc.  2023 Jan;56(1):132-134. 10.5946/ce.2022.298.

A rapidly growing round mass in the gallbladder

Affiliations
  • 1Division of Gastroenterology, Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea
  • 2Division of Gastroenterology and Hepatology, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang University School of Medicine, Cheonan, Korea


Figure

  • Fig. 1. Abdomen computed tomography (CT) findings. (A) Enhanced CT showed focal enhancement and wall thickening on the fundus (yellow arrow) of the gallbladder without disruption of the wall layer. (B) A follow-up CT showed similar findings, but with enlarged enhancing wall thickening and a hypodense lesion on the gallbladder fundus (yellow arrow). Direct liver invasion or wall disruption of the gallbladder was not definitive.

  • Fig. 2. Endoscopic ultrasound image shows about 2×1 cm sized elliptical wall thickening without disruption of the wall layer. Internal echogenicity was mixed with diffuse hyperechoic spots and hypoechoic lesions.

  • Fig. 3. Pathologic features of the resected specimen. (A) A Low-power field (hematoxylin and eosin stain, ×10) showed Rokitansky-Aschoff sinuses resulting from hyperplasia and herniation of epithelial cells through the fibromuscular layer of the gallbladder wall. (B) A high-power field (hematoxylin and eosin stain, ×100) revealed abundant infiltration of foamy histiocytes, lymphocytes, and multinucleated giant cells.


Reference

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3. Agarwal AK, Kalayarasan R, Javed A, et al. Mass-forming xanthogranulomatous cholecystitis masquerading as gallbladder cancer. J Gastrointest Surg. 2013; 17:1257–1264.
4. Makimoto S, Takami T, Hatano K, et al. Xanthogranulomatous cholecystitis: a review of 31 patients. Surg Endosc. 2021; 35:3874–3880.
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