Infect Chemother.  2022 Dec;54(4):803-807. 10.3947/ic.2020.0206.

Liver Abscess caused by Cytomegalovirus in a Patient with Acquired Immunodeficiency Syndrome

• Lee JY
• Park Jw
• Park JY

• KMID: 2537718
• DOI: http://doi.org/10.3947/ic.2020.0206

Abstract

Cytomegalovirus (CMV) causes severe infection in immunocompromised patients, especially those with acquired immunodeficiency syndrome (AIDS), those who have undergone organ transplantation, and/or those who are being treated with steroids. In patients with AIDS, CMV is the most common pathogen that causes opportunistic infections. Here, we present a case of liver abscess due to CMV in a 58-year-old man diagnosed with AIDS. At the time of the study, his CD4 T lymphocyte count was 39 cells/mm ³ , and his human immunodeficiency virus (HIV) ribonucleic acid (RNA) level was 411,000 copies/mL. Upon presentation, he complained of upper abdominal pain. Ultrasonography-guided percutaneous drainage of the liver abscess was performed, and polymerase chain reaction analysis of the drained pus was positive for CMV. He was treated with intravenous ganciclovir, after which he recovered fully. In conclusion, our patient represents, to our knowledge, the first described case of liver abscess caused by CMV in an AIDS patient, which was probably facilitated by severe immunodeficiency.

Keyword

Cytomegalovirus; Acquired immunodeficiency syndrome; Liver abscess