Urogenit Tract Infect.
2022 Dec;17(3):81-88. 10.14777/uti.2022.17.3.81.
Korean Multicenter Study of Infectious Complications after Transurethral Prostate Surgery in Patients with Preoperative Sterile Urine
- Affiliations
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- 1Department of Urology, Chonnam National University Medical School, Gwangju, Korea
- 2Department of Urology, Chung-Ang University College of Medicine, Seoul, Korea
- 3Department of Urology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea
- 4Department of Urology, College of Medicine, Kyung Hee University, Seoul, Korea
- 5Department of Urology, College of Medicine, Konyang University, Daejeon, Korea
- 6Department of Urology, The Catholic University of Korea, Uijeongbu St. Maryʼs Hospital, Seoul, Korea
- 7Department of Urology, Veterans Health Service Medical Center, Seoul, Korea
- 8Department of Urology, The Catholic University of Korea, Incheon St. Mary’s Hospital, Incheon, Korea
- 9Department of Urology, Goldman Urologic Clinic, Seoul, Korea
- 10Department of Urology, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea
- KMID: 2537605
- DOI: http://doi.org/10.14777/uti.2022.17.3.81
Abstract
- Purpose
To evaluate the efficacy of antibiotic prophylaxis and determine the risk factors of infectious complications after transurethral surgery of the prostate.
Materials and Methods
Seven hundred and seventy-two patients who underwent transurethral resection of the prostate (TURP) or holmium laser enucleation of the prostate (HOLEP) were reviewed. Of these, this study enrolled 643 patients without bacteriuria who had not received antibiotics for urinary tract infections for two weeks before surgery. The patients were divided into two groups according to the duration of the antibiotics (Group 1: less than one day, n=396 vs. Group 2: more than one day, n=247).
Results
The overall incidence of postoperative infectious complications in 643 patients was 5.0% (32/643). When postoperative infectious complications were compared according to the duration of the antibiotics (Group 1 vs. Group 2), the infectious complications rates were 5.6% (22/396) vs. 4.0% (10/247), respectively (p=0.393). When postoperative infectious complications were compared according to the duration of antibiotics (Group 1 vs. Group 2) in the TURP and HOLEP groups, the infectious complications rates were 6.3% (12/192) vs. 1.0% (1/103) (p=0.035) and 4.9% (10/203) vs. 6.0% (8/134) (p=0.677), respectively. The duration of Foley catheterization was independently associated with infectious complications (p=0.003).
Conclusions
The results showed that prolonged postoperative catheterization affects postoperative infectious complications associated with transurethral prostate surgery. Although antibiotics administered for less than one day are effective for antibiotic prophylaxis of transurethral prostate surgery, a longer antibiotic therapy is recommended for TURP.
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