Cardiovasc Prev Pharmacother.  2019 Oct;1(2):50-56. 10.36011/cpp.2019.1.e9.

Pregnancy at Late Maternal Age and Future Cardiovascular Health

Affiliations
  • 1Department of Cardiovascular Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea
  • 2Department of Cardiology, College of Medicine, The Catholic University of Korea, Seoul, Korea

Abstract

Increasing numbers of women are delivering their first child at a later age. First pregnancy at a later age is, per se, a high-risk pregnancy. Pregnancy after 35 years is traditionally considered a late maternal age. The risks of obstetric complications including fetal and maternal complications are increased. Defective placenta syndrome, including hypertensive disorders, preterm birth, and intrauterine growth retardation, shares similar pathophysiologic mechanisms with endothelial dysfunction, although their clinical presentations differ. Recent medical advances have improved the medical performance of pregnancy-related cardiovascular disease (CVD). Recent evidence has shown that women with underlying defective placental syndrome or other pregnancy-related complications have an increased risk of unfavorable cardiovascular outcomes in later life. An increasing number of women delivering their first child at a later age have epidemiological characteristics that differ from those reported previously and for which data are limited data regarding the cardiovascular prognosis. Therefore, increased attention to public health and CVD prevention is required for women with complicated pregnancies.

Keyword

Cardiovascular diseases; Pregnancy; Pregnancy complications, cardiovascular; Pregnant women; Women

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