Korean J Head Neck Oncol.  2022 Nov;38(2):37-41. 10.21593/kjhno/2022.38.2.37.

A Case of Squamous Cell Carcinoma arising from an Odontogenic Keratocyst

• Oh JE
• Lee CY
• Kim KM
• Tak MS
• Byeon HK

• KMID: 2536620
• DOI: http://doi.org/10.21593/kjhno/2022.38.2.37

Abstract

Odontogenic keratocyst (OKC) accounts for 3-11% of all odontogenic cysts. OKC is a benign intra-osseous odontogenic tumor, but what makes this cyst special is its aggressive behavior and high recurrence rate. OKC is relatively aggressive compared to other odontogenic cysts, but its malignant transformation is considered extremely rare. Squamous cell carcinoma associated with odontogenic keratocysts have rarely been reported in the medical literature. We recently experienced a case of a 63-year-old man finally confirmed with squamous cell carcinoma of the mandible, which was initially diagnosed as a benign odontogenic keratocyst. Surgical resection was performed as definitive treatment. Therefore, we present this unique case with a review of the literature.

Keyword

Odontogenic keratocyst; Odontogenic tumors; Keratocystic odontogenic tumor; Squamous cell carcinoma of mandible