Korean J Transplant.  2022 Nov;36(Supple 1):S190. 10.4285/ATW2022.F-3180.

Outcomes of heart transplantation according to allocation region

Affiliations
  • 1Department of Thoracic and Cardiovascular Surgery, Pusan National University Yangsan Hospital, Yangsan, Korea
  • 2Department of Cardiology, Pusan National University Yangsan Hospital, Yangsan, Korea

Abstract

Background
The Korean donor heart allocation system divides the region into three, and recipients of heart transplantation (HT) in the same status have priority of the donor in the same region. Generally, it is thought that HT of intra-region can reduce ischemic time, however, its clinical impact is unclear. The purpose of this study is to compare the characteristics and outcomes of intra-region HT and inter-region HT.
Methods
From June 2014 to July 2022, a total 111 patients underwent HT at a single institution. Of these, 91 cases were adult (>18 year) isolated HT and enrolled present study (pediatric HT, 13 cases; multiple transplantation, 7 cases). Of subjects, 45 cases were intra-regional HT, and 46 cases were inter-regional HT.
Results
Preoperative recipient′s characteristics were no difference between two groups. Ratio of male donor was higher in intra-regional group (80.0% vs. 58.7%, P=0.048). The cold and total ischemic times were longer (approximately 2 hours) in in-ter-regional group (P<0.001). Other donor′s profiles were similar in two groups. There was no difference of early clinical out-comes between both groups. And postoperative cardiac index and vasoactive inotropic score were also no difference in two groups. In addition, the long-term survival rate was no difference in two group (P=0.23).
Conclusions
In our experience, about half of whole HTs were performed with donors from other regions in the present Korean allocation system. Despite interregional HT takes an average of 2 hours longer ischemic time than intraregional HT, there was no difference in postoperative results between the two groups. According to the present study, the clinical impact of donor location on the outcome of recipient in the domestic HT is not considered to be significant.

Full Text Links
  • KJT
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr