Korean J Transplant.  2022 Nov;36(Supple 1):S102. 10.4285/ATW2022.F-2220.

Recent perioperative blood transfusion in elective kidney transplantation

• Roh J
• Park S
• Kang YJ
• Kang HJ

• KMID: 2535618
• DOI: http://doi.org/10.4285/ATW2022.F-2220

Abstract

Background
Forecasting an appropriate demand for blood transfusion is essential for a blood bank. Balancing supply and de-mand is a key factor for effective and efficient blood product inventory management. Due to the risk of an emergency such as massive bleeding during transplantation surgery, it is necessary for the blood bank to maintain an adequate level of blood prod-uct inventory. In this study, we analyzed the perioperative transfusions in elective kidney transplantation patients.
Methods
Data of all complement-dependent cytotoxicity-crossmatched assays between the year 2013 and the year 2022 were collected. We excluded duplicates in case of a repeated assay in one patient and we excepted the patients who did not undergo kidney transplantation. Transfusion records such as a number of blood products and transfusion adverse reactions were reviewed retrospectively.
Results
A total of 30 patients were undergone elective kidney transplantation from the year 2015 to the year 2022. The mean age of the patients was 48.07 years. The male to female ratio was 1.5:1. Four patients were transfused intraoperatively, whereas eight patients were transfused postoperatively. The postoperative hemoglobin level of the transfusion group was significantly lower than that of the non-transfusion group. Postoperative platelet count, PT INR, and aPTT concentration were not significantly different between the two groups. Leuko-reduced filtered red blood cells were most transfused intraoperatively followed by fresh frozen plasma. As a result of dividing the study period into the first half and the second half according to the time of operation, there were more cases of significant transfusion in the first half.
Conclusions
In most cases of elective kidney transplantation, surgery was performed without blood transfusion, and the transfusion time was changed from intraoperative to postoperative. The introduction of patient blood management along with the development of surgical techniques seems to have influenced the perioperative transfusion pattern.