Korean J Transplant.  2022 Nov;36(Supple 1):S352. 10.4285/ATW2022.F-4960.

Living donor liver transplantation postoperative donor follow-up

• Badarch BI
• Tuul M
• Ganbaatar B
• Sainbuyan T

• KMID: 2535579
• DOI: http://doi.org/10.4285/ATW2022.F-4960

Abstract

Background
Mongolia has the highest prevalence of hepatitis B virus (HBV), hepatitis C virus (HCV), and hepatitis D virus infection. The prevalence of HCV was 18.9%. Additionally, HBV infection was observed in 23.1% and 1.2% were coinfected with HCV and HBV in Mongolia. Mongolia has the highest HCC incidence in the world (78.1/100,000, 3.5* higher than China).
Methods
Of the 156 intended living donors, who had applied for liver donation, living donor liver transplantation (LDLT) surgery was performed at First Central Hospital of Mongolia from September, 2011 to September, 2020. All donors were healthy adults and kin to the recipients. The in-hospital and follow-up data was acquired from the patient records and the Organ Transplanta-tion Center of First Central Hospital of Mongolia. The living donor morbidity was graded according to the modified Clavien-Dindo classification system.
Results
Therefore, LDLT was performed 156 donors, 91 male donors (57.9%). The median age of the donors was 32.7±9.03 years (range, 18–49 years). Most donors (151, 96.7%) donated the right lobe liver. The remnant volume of the right lobe of the liver donor is 713.7±152.4 g (59.42%), the remnant volume of the remaining liver is 487 g (40.58%). The average duration of LDLT is 6 hours 38 minutes±2 hours 2 minutes, and the intensive care bed is 5.4±2.4 days. Total bilirubin (1.18 mg/dL), alanine aminotrans-ferase (ALT; 204.9 U/L), aspartate aminotransferase (AST; 224.07 U/L) increased from the first postoperative day of LDLT sur-gery in all donors, on the seventh day after surgery total bilirubin (0.82 mg/dL), ALT (50.84 U/L), AST (72.69 U/L) decreased too normal. All the donors have led a normal life after donation postoperation seventh–tenth day. Only one case had a complication Clavien-Dindo Classification Grade3b, which is portal vein stenosis. Totally five deliveries had during these 10 years. There was no postoperative mortality.
Conclusions
As far the liver donor survival rate after liver transplantation in our hospital is 100% since the first transplantation. Living donor liver transplantation is relatively safe for donors and severe postoperation complication is rare.