Factors associated with quality of life after kidney transplantation: a cross-sectional study
- Affiliations
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- 1Department of Internal Medicine, Dr. Cipto Mangunkusumo National Central Public Hospital, Jakarta, Indonesia
Abstract
- Background
Kidney transplantation is currently the best choice for renal replacement therapy, it reduces the risk of death and increases the survival rates compared with conservative therapy and is also known to improve health-related quality of life (QoL) from various aspects, especially physical health and aspects of psychosocial functioning. This study aims to determine and identify factors associated with QoL after kidney transplantation.
Methods
This is a cross-sectional study conducted in Dr. Cipto Mangunkusumo National Central Public Hospital. We enrolled 107 consecutive subjects who received kidney transplantation from January 2018 to December 2020. All participants had the same evaluations which QoL was performed by the 36-Item Short Form Health Survey (SF-36) questionnaire. Univariate, bivari-ate, and multivariate analyzes were performed on the independent variables and dependent variable (SF-36).
Results
Duration of dialysis, hemoglobin levels, Eastern Cooperative Oncology Group (ECOG) status, and depression were con-tributed to the physical component summary component of QoL (R 2 =21.4%) while hemoglobin levels and depression contributed to the mental component summary component (R 2 =33.6%). And factors related to total score of SF-36 were hemoglobin levels, ECOG status, and depression (R 2 =40.7%). Factors that contributed and were statistically significant to QoL status were hemoglo-bin levels, ECOG status, and depression.
Conclusions
The results of the study can support the need for an assessment of the quality of life as a regular basis in patients before and after kidney transplantation.