Korean J Transplant.  2022 Nov;36(Supple 1):S50. 10.4285/ATW2022.F-1653.

Intragraft Kaposi’s sarcoma after kidney transplantation: a case report

• Lee JJ
• Shin S
• Kim YH
• Kwon H
• Ko Y
• Kwon HE
• Choi M
• Kim JM
• Jung JH

• KMID: 2535254
• DOI: http://doi.org/10.4285/ATW2022.F-1653

Abstract

Although Kaposi’s sarcoma is rare disease, it has a high prevalence in solid organ transplant recipients. Especially in South Korea, the expected prevalence of Kaposi’s sarcoma after kidney transplantation was reported to be higher than in other posttransplantation de novo cancers. Skin is the most common site for Kaposi’s sarcoma. However, we have confirmed intragraft Kaposi’s sarcoma after kidney transplantation and would like to review it. A 53-year-old female who had been on dialysis due to diabetic nephropathy underwent a deceased donor kidney transplantation on December 7, 2021. About 10 weeks after kidney transplantation, the level of serum creatinine increased from 1.77 mg/dL to 2.99 mg/dL. Computerized tomography showed hydronephrosis with kinking in allograft ureter. So percutaneous nephrostomy followed by anterograde double J stent insertion was performed. During the procedure, bleeding due to a renal artery branch injury occurred. Therefore, percutaneous emboliza-tion of one branch of renal artery was performed. After embolization, she developed uncontrolled fever due to kidney allograft necrosis. Eventually graftectomy was performed to overcome septic shock. On surgical findings, the kidney parenchyme was necrotic as a whole and lymphoproliferative lesion were infiltrated diffusely in the allograft. In addition, multiple lymphadenopathy was observed around iliac artery. The pathologic report confirmed Kaposi’s sarcoma in kidney allograft as well as in adjacent lymph nodes. we report a rare case in which a recipient developed Kaposi’s sarcoma in kidney allograft as well as in adjacent lymph nodes.