Lab Med Qual Assur.
2022 Sep;44(3):181-184. 10.15263/jlmqa.2022.44.3.181.
False Elevation of the Concentration of ThyroidStimulating Hormone: A Case Report
- Affiliations
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- 1Departments of Laboratory Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea
- 2Departments of Pediatrics, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea
- KMID: 2534083
- DOI: http://doi.org/10.15263/jlmqa.2022.44.3.181
Abstract
- Analytical errors owing to endogenous interfering substances may occur for some patient specimens. Interference can lead to false-positive or falsenegative results, or both, which may lead to a false diagnosis or inappropriate treatment. We report a case of false elevation of thyroid-stimulating hormone concentrations measured using an electrochemiluminescent immunoassay in a clinically euthyroid 10-year-old Korean boy with central precocious puberty. If the clinical presentations and test results of a patient are inconsistent, a clinician should suspect interference in clinical laboratory tests.
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