Asian Oncol Nurs.  2022 Sep;22(3):127-135. 10.5388/aon.2022.22.3.127.

Factors Influencing Compliance with Safe Handling Requirements of Antineoplastic Agents by Nurses in a Tertiary Hospital

• Lee SG
• Choi SY

• KMID: 2533970
• DOI: http://doi.org/10.5388/aon.2022.22.3.127

Abstract

Purpose
The research aimed to identify leading factors that affect a nurse’s compliance with safe handling in the use of antineoplastic agents.
Methods
Data were collected from 114 nurses working in the university hospital. Data were analyzed through independent t-test, one-way ANOVA, Pearson’s correlation coefficient and multiple regression analysis using SPSS WIN 25.0.
Results
The average level of compliance with safe handling of antineoplastic agents was 3.73±0.33 out of 5 points. Workplace safety climate (β=.40, p<.001) and knowledge of safe handling (β=.18, p=.030) had significant influences on nurses’ compliance with safe handling of antineoplastic agents. The explained variance for compliance was 28.3%.
Conclusion
To enhance the implementation of safety management for antineoplastic agents, each institution should strive to support human and material resources and to enhance specialization in the workplace safety climate through system improvement. Based on the results of this study, we suggest research for the development of an antineoplastic agents safety management training program.

Keyword

Antineoplastic agents; Compliance; Knowledge; Nurse; Safety