Investig Magn Reson Imaging.  2022 Sep;26(3):166-170. 10.13104/imri.2022.26.3.166.

Two Cases of Herlyn-Werner-Wunderlich Syndrome

• Kim Y
• Ku YM
• Won YD

• KMID: 2533885
• DOI: http://doi.org/10.13104/imri.2022.26.3.166

Abstract

Herlyn-Werner-Wunderlich (HWW) syndrome—also known as obstructed hemivagina and ipsilateral renal anomaly—is a rare congenital anomaly of Müllerian ducts and Wolffian ducts which is classically characterized by uterine didelphys, obstructed hemivagina, and ipsilateral renal agenesis; however, there are various combinations of uterine anomalies, obstruction sites, and renal anomalies that can occur as anatomic variants of HWW syndrome. Most patients show symptoms of recurrent lower abdominal pain or pelvic mass after the onset of menarche. Diagnosis can be delayed due to regular menstruation through non-obstructed hemivagina, which can lead to complications such as endometriosis, pyocolpos, pelvic inflammatory disease, and infertility. Here, we report two cases of females who presented dysmenorrhea and pelvic mass after the onset of puberty and were diagnosed with HWW syndrome through pelvic MRI. A review of the relevant literature was also provided.

Keyword

Mullerian Ducts; Uterus; Magnetic resonance imaging