Med Lasers.  2022 Mar;11(1):40-46. 10.25289/ML.2022.11.1.40.

A Comparison of the Effects of Solid-state Lasers on Normal Guinea-pig Muscle and Skin: Using 532 nm Flashlamp-excited and Diode-excited Lasers

• Kim YA
• Jung GJ
• Choi HR
• Kim JS
• Lee SJ
• Chung PS
• Woo SH

• KMID: 2533544
• DOI: http://doi.org/10.25289/ML.2022.11.1.40

Abstract

Background and Objectives
Pulsed Nd:YAG lasers have been used in various medical fields and show high second harmonic generation efficiency at 532 nm. The pulse duration at 532 nm varies from 10 ns to 1000 ns, depending on the excitation method. This study aimed to compare the effects of 100 ns and 600 ns, 532 nm flashlamp excited solid (FPSS) and diode excited solid (DPSS) lasers on guinea pig muscles and skin.
Materials and Methods
Experiments were carried out on the guinea pig muscles and skin. First, the guinea pig muscles, and skin were irradiated with 532 nm FPSS and DPSS lasers at varying intensities and periods. A visual examination of the muscle lesions and an immediate histopathological examination of the skin were performed.
Results
When guinea pig muscles were irradiated with FPSS and DPSS lasers, the degree of light evaporation and photo necrosis was much higher with the FPSS laser. There was also higher guinea pig muscle and skin vaporization and necrosis with the FPSS laser than with the DPSS laser when both lasers were used to irradiate the guinea pig skin at power levels of 1 watt (63.7 J/cm² ), 2 watts (127.3 J/cm² ), 4 watts (254.6 J/cm² ), and 8 watts (509.3 J/cm² ).
Conclusion
The DPSS laser system appears to be more effective and even safer than the FPSS laser system; it delivers more satisfactory surgical results and causes less serious damage to the surrounding tissue.

Keyword

Laser; Vaporization; Necrosis