J Korean Med Sci.  2022 Aug;37(30):e221. 10.3346/jkms.2022.37.e221.

Case 2: A 66-Year-Old Man With Chronic Watery Diarrhea

• Shin JE
• Youn SY
• Kim Y
• Lee M
• Park SJ

• KMID: 2532226
• DOI: http://doi.org/10.3346/jkms.2022.37.e221

Figure

• 

  Fig. 1 Abdominal imaging and 18F-DOPA PET/CT. An axial image from a contrast enhanced CT scans of abdomen and pelvis (A) shows a 5.2cm sized pancreatic tail mass (arrow) with central hypodense portion. Axial arterial phase T1-weighted fat-suppressed magnetic resonance image (B) shows the mass (arrow) with marked enhanced peripheral solid mass with central cystic change and hemorrhage with fluid-fluid level (arrowhead). 18F-DOPA PET/CT image (C, D) clearly depicts a pancreatic tail tumor (arrow) with peripheral uptake and central photon defect.

• 

  Fig. 2 Pathological findings. A specimen obtained from surgical resection of the pancreatic tail shows cystic mass that measured 5.0 × 4.8 × 4.4 cm (A, B). Microscopical examination of a section of the pancreatic mass shows tumor cells with small, round to ovoid nucleus and disperse chromatin which arranged in nesting and trabecular pattern (C, hematoxylin and eosin, ×100). Mitosis was up to 1 per 10 high power fields. Immunohistochemical staining revealed positivity for synaptophysin (D) and negativity for chromogranin (E). Ki-67 proliferation index was 2% (F).

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