J Korean Neurol Assoc.  2022 Aug;40(3):243-246. 10.17340/jkna.2022.3.5.

CLOCC Patient after COVID-19 (BNT162b) Vaccine Improved by Steroid Treatment

Affiliations
  • 1Department of Neurology, Hanyang University Guri Hospital, Guri, Korea

Abstract

Cytotoxic lesions of the corpus callosum (CLOCC) are secondary lesions on corpus callosum caused by cytokinopathy of callosal neurons and microglia. Fever, headache, and digestive disturbances are common symptoms. Reversible and hyperintense signals on fluid‐attenuated inversion recovery imaging, diffusion‐weighted imaging (DWI) and decreased apparent diffusion coefficient are typical features of magnetic resonance imaging. Herein, we report a rare case of CLOCC caused by COVID19 vaccination (BNT162b) and discharged without no neurologic symptoms due to prompt treatment.

Keyword

Cytotoxic lesions of the corpus callosum; COVID19 vaccination; Steroid therapy
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