J Korean Med Sci.  2022 Jul;37(26):e206. 10.3346/jkms.2022.37.e206.

The Association Between Bacille Calmette-Guérin Vaccination and Nontuberculous Mycobacterial Pulmonary Disease

• Kwak N
• Hwang HW
• Kim HJ
• Lee HW
• Yim JJ
• Lee CH

• KMID: 2531038
• DOI: http://doi.org/10.3346/jkms.2022.37.e206

Abstract

This study aimed to investigate the association between Bacille Calmette-Guérin (BCG) vaccination and nontuberculous mycobacterial pulmonary disease (NTM-PD). Patients in the prospective NTM-PD cohort were matched to healthy controls to measure the association between BCG and NTM-PD development. The clinical course of NTM-PD patients was also evaluated to investigate the association between BCG and NTM-PD progression. BCG scars were not associated with NTM-PD development (adjusted odds ratio [OR], 2.04; 95% confidence interval [CI], 0.96–4.34) or progression (adjusted OR, 1.61; 95% CI, 0.92–2.81). In conclusion, BCG vaccination was not associated with the development or progression of NTM-PD.

Keyword

Bacille Calmette-Guérin; Vaccination; Nontuberculous Mycobacteria

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