Korean J Fam Pract.  2022 Jun;12(3):144-150. 10.21215/kjfp.2022.12.3.144.

Relationship between Health Behaviors and Metabolic Syndrome in Cancer Survivors in Korea: Korean National Health and Nutrition Examination Survey, 2013–2018

• Kim N
• Kim S
• Choi BG
• Ko YU
• Park Ka

• KMID: 2530655
• DOI: http://doi.org/10.21215/kjfp.2022.12.3.144

Abstract

Background
This study was conducted to evaluate whether cigarette smoking and alcohol drinking were associated with metabolic syndrome in cancer survivors.
Methods
Using Korea National Health and Nutrition Examination Survey (KNHANES) from 2013 through 2018, a total of 1,421 cancer survivors (male 533, female 888; aged ≥19 y), were included in this study. To assess the association between smoking, alcohol drinking, and metabolic syndrome, adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using multiple logistic regression analysis. The analysis included the following covariates: age, age at cancer diagnosis, marital status, educational status, average monthly income of households, level of stress, walking exercise, and BMI.
Results
Among male participants, current smokers were 3.04 times more likely to develop metabolic syndrome (OR, 3.04; 95% CI, 1.52–6.07), and components of metabolic syndrome, such as high waist circumference, hypertriglyceridemia, and hypo-high-density lipoprotein (HDL) cholesterolemia were particularly affected (OR 2.71, 95% CI 1.06–6.96; OR 1.95, 95% CI 1.07–3.56; OR 2.53, 95% CI 1.35–4.75, respectively). High risk drinking increased the risk of hypertriglyceridemia (OR, 2.11; 95% CI, 1.06–4.21) and impaired fasting blood glucose (OR, 2.29; 95% CI, 1.06–4.95) in male and hypertension in female (OR, 3.50; 95% CI, 1.08–11.35).
Conclusion
In this study, we found that current smoking was independently related to metabolic syndrome in male cancer survivors, while high risk drinking increased the risk of components of metabolic syndrome in both male and female cancer survivors.

Keyword

Cancer Survivors; Smoking; Alcohol Drinking; Metabolic Syndrome