J Korean Assoc Oral Maxillofac Surg.  2022 Apr;48(2):117-121. 10.5125/jkaoms.2022.48.2.117.

A diagnostic dilemma in pediatric osteomyelitis: a case report

Affiliations
  • 1Department of Oral and Maxillofacial Surgery, Goa Dental College & Hospital, Bambolim, India
  • 2Department of Oral and Maxillofacial Pathology, Goa Dental College & Hospital, Bambolim, India

Abstract

Infantile osteomyelitis is a rare disease that is infective in nature and may rapidly turn fatal, as the disease is often misdiagnosed due to its varied presenting signs. Early diagnosis may help in avoiding systemic involvement and permanent deformity. The disease presents with signs of orbital involvement, nasal congestion, and emesis, as well as other standard hallmarks of infection. Furthermore, the maxilla is a highly vascular and porous bone and the occurrence of osteomyelitis in an infant maxilla is highly uncommon. In addition, routine blood work is not suggestive of the presence of this disease. Thus, prompt diagnosis of this condition poses a challenge to surgeons due to the confusing array of symptoms combined with the rarity of the disease. One such case of osteomyelitis of the maxilla in a young child is presented. The dilemma encountered by the surgeon during the diagnosis and treatment of the disease is discussed.

Keyword

Osteomyelitis; Cellulitis; Pediatric; Maxillofacial; Infection

Figure

  • Fig. 1 Showing excessive scleral show and scar in relation to right eye.

  • Fig. 2 Intraoral infected site exposing the underlying bone.

  • Fig. 3 Computed tomography scan showing axial section (A), coronal section (B), and three-dimensional view (C).

  • Fig. 4 Exposure of the infected bone.

  • Fig. 5 Removal of the infected tissue till healthy bone is exposed.

  • Fig. 6 H&E stained sections of the specimen (A: ×4, B: ×10, C: ×4, D: ×10).

  • Fig. 7 Removal of involved teeth and underlying tissue obtained for histopathological examination.

  • Fig. 8 Postoperative healing site.


Reference

References

1. Dieckmann R, Hardes J, Ahrens H, Flieger S, Gosheger G, Götze C, et al. 2008; [Treatment of acute and chronic osteomyelitis in children]. Z Orthop Unfall. 146:375–80. German. https://doi.org/10.1055/s-2008-1038461. DOI: 10.1055/s-2008-1038461. PMID: 18561085.
Article
2. Korakaki E, Aligizakis A, Manoura A, Hatzidaki E, Saitakis E, Anatoliotaki M, et al. 2007; Methicillin-resistant Staphylococcus aureus osteomyelitis and septic arthritis in neonates: diagnosis and management. Jpn J Infect Dis. 60:129–31. PMID: 17515648.
3. Feng Z, Chen X, Cao F, Lai R, Lin Q. 2015; Osteomyelitis of maxilla in infantile with periorbital cellulitis: a case report. Medicine (Baltimore). 94:e1688. https://doi.org/10.1097/MD.0000000000001688. DOI: 10.1097/MD.0000000000001688. PMID: 26448016. PMCID: PMC4616730.
Article
4. Khullar SM, Tvedt D, Chapman K, Herlofson BB. 2012; Sixty cases of extreme osteonecrosis and osteomyelitis of the mandible and maxilla in a West African population. Int J Oral Maxillofac Surg. 41:978–85. https://doi.org/10.1016/j.ijom.2012.04.022. DOI: 10.1016/j.ijom.2012.04.022. PMID: 22652445.
Article
5. Goodé-Jolly D, Besson D, Lopez A, Cabanis EA. 1986; [A case of acute osteomyelitis of the maxilla in infants. Current prognosis of ocular and dental manifestations]. Bull Soc Ophtalmol Fr. 86:1141–4. French. PMID: 3581314.
6. Yadav S, Malik S, Mittal HC, Puri P. 2014; Chronic suppurative osteomyelitis of posterior maxilla: a rare presentation. J Oral Maxillofac Pathol. 18:481. https://doi.org/10.4103/0973-029X.151364. DOI: 10.4103/0973-029X.151364. PMID: 25949012. PMCID: PMC4409202.
Article
7. Loh FC, Ling SY. 1993; Acute osteomyelitis of the maxilla in the newborn. J Laryngol Otol. 107:627–8. https://doi.org/10.1017/s0022215100123916. DOI: 10.1017/S0022215100123916. PMID: 15125285.
Article
8. Skouteris CA, Velegrakis G, Christodoulou P, Helidonis E. 1995; Infantile osteomyelitis of the maxilla with concomitant subperiosteal orbital abscess: a case report. J Oral Maxillofac Surg. 53:67–70. https://doi.org/10.1016/0278-2391(95)90505-7. DOI: 10.1016/0278-2391(95)90505-7. PMID: 7799125.
Article
9. Lieberman H, Brem J. 1959; Syndrome of acute osteomyelitis of the superior maxilla in early infancy. N Engl J Med. 260:318–22. https://doi.org/10.1056/NEJM195902122600704. DOI: 10.1056/NEJM195902122600704. PMID: 13632884.
Article
10. Wilensky AO. 1932; Osteomyelitis of the jaws in nurslings and infants. Ann Surg. 95:33–45. https://doi.org/10.1097/00000658-193201000-00003. DOI: 10.1097/00000658-193201000-00003. PMID: 17866715. PMCID: PMC1391555.
Article
11. Scott EP, Rotondo CC. 1946; Fracture with osteomyelitis of the mandible in a newborn infant. Am J Dis Child. 72:411–4. https://doi.org/10.1001/archpedi.1946.02020330043006. DOI: 10.1001/archpedi.1946.02020330043006. PMID: 20275870.
Article
12. Sanders B. 1979. Pediatric oral and maxillofacial surgery. Mosby;St. Louis (MO): p. 195. DOI: 10.1001/archpedi.1946.02020330043006.
13. Thoma KH. 1969. Oral surgery. 5th ed. Mosby;St. Louis (MO): p. 781. DOI: 10.1001/archpedi.1946.02020330043006.
14. Davis CH. 1940. Davis᾿ gynecology and obstetrics. Vol. 2:W. F. Prior Company;Hagerstown (MD): p. 31. DOI: 10.1001/archpedi.1946.02020330043006.
15. Kang HJ, Lee JH, Kim YD, Byun JH, Shin SH, Kim UK, et al. 2004; Osteomyelitis occuring in the zygoma caused by odontogenic maxillary sinusitis - case report. J Korean Assoc Oral Maxillofac Surg. 30:251–4.
16. Street M, Puna R, Huang M, Crawford H. 2015; Pediatric acute hematogenous osteomyelitis. J Pediatr Orthop. 35:634–9. https://doi.org/10.1097/BPO.0000000000000332. DOI: 10.1097/BPO.0000000000000332. PMID: 25333907.
Article
Full Text Links
  • JKAOMS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr