J Korean Med Sci.  2022 May;37(18):e147. 10.3346/jkms.2022.37.e147.

Outcomes of Late-Preterm and Term Infants Born to SARS-CoV-2-Positive Mothers

  • 1Department of Pediatrics, National Medical Center, Seoul, Korea
  • 2Research Institute for Public Healthcare, National Medical Center, Seoul, Korea
  • 3Department of Obstetrics and Gynecology, National Medical Center, Seoul, Korea


With the spread of coronavirus disease 2019 (COVID-19) in Korea, the number of pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is rapidly increasing. A shortage of negative-pressure isolation rooms for newborns makes hospital assignment more difficult for late-pregnant women with COVID-19. Among 34 infants born to SARS-CoV-2-positive mothers, 5 (14.7%) presented with respiratory distress and 1 (2.9%) presented with feeding intolerance that required specialized care. Aerosolgenerating procedures were performed in one infant. Overall outcomes of 34 infants were favorable, and no infant tested positive for SARS-CoV-2. Most infants born to SARS-CoV-2-positive mothers did not need to be quarantined in a negative-pressure isolation room, and 17 (50%) mother–infant dyads were eligible for rooming-in. If negative-pressure isolation rooms are selectively used for newborns requiring aerosol-generating procedures or newborns in respiratory distress, resource availability for lower-risk cases may improve.


COVID-19; SARS-CoV-2; Pregnancy; Infant; Newborn; Disease Transmission; Infectious; Negative-Pressure Isolation


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