Korean J Radiol.
2022 May;23(5):517-528. 10.3348/kjr.2021.0596.
Low-Dose Abdominal CT for Evaluating Suspected Appendicitis in Adolescents and Young Adults: Review of Evidence
- Park JH
1,2,3 - Salminen P4,5
- Tannaphai P6
- Lee KH1,2,3,7
- Affiliations
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- 1Department of Radiology, Seoul National University Bundang Hospital, Seongnam, Korea
- 2Department of Applied Bioengineering, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Korea
- 3Department of Radiology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
- 4Department of Surgery, University of Turku, Turku, Finland
- 5Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland
- 6Department of Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
- 7Interdisciplinary Program in Bioengineering, Seoul National University, Seoul, Korea
- KMID: 2529283
- DOI: http://doi.org/10.3348/kjr.2021.0596
Abstract
- Due to its excellent diagnostic performance, CT is the mainstay of diagnostic test in adults with suspected acute appendicitis in many countries. Although debatable, extensive epidemiological studies have suggested that CT radiation is carcinogenic, at least in children and adolescents. Setting aside the debate over the carcinogenic risk of CT radiation, the value of judicious use of CT radiation cannot be overstated for the diagnosis of appendicitis, considering that appendicitis is a very common disease, and that the vast majority of patients with suspected acute appendicitis are adolescents and young adults with average life expectancies. Given the accumulated evidence justifying the use of low-dose CT (LDCT) of only 2 mSv, there is no reasonable basis to insist on using radiation dose of multi-purpose abdominal CT for the diagnosis of appendicitis, particularly in adolescents and young adults. Published data strongly suggest that LDCT is comparable to conventional dose CT in terms of clinical outcomes and diagnostic performance. In this narrative review, we will discuss such evidence for reducing CT radiation in adolescents and young adults with suspected appendicitis.
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