Endocrinol Metab.  2022 Apr;37(2):383-385. 10.3803/EnM.2022.1437.

Transarterial Radioembolization as an Effective Local Treatment Modality for Liver Metastasis of Thyroid Cancer

Affiliations
  • 1Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
  • 2Department of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
  • 3Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
  • 4Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
  • 5Department of Otolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
  • 6Department of Nuclear Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
  • 7Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Korea


Figure

  • Fig. 1. (A) A dynamic computed tomography (CT) scan of the hepatic arterial phase performed before transarterial radioembolization (TARE) shows heterogeneous enhancement (low in the central area and high in peripheral area) of liver metastases (red arrows). (B) An 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/CT scan at the same level shows metastatic masses with hypermetabolism (red arrows). (C) A common hepatic angiogram shows minimal hypervascularity of liver metastases (red circle with dotted line). (D) PET/CT immediately after TARE shows high radioactivity within the tumor (red arrows). (E) A CT scan of the hepatic arterial phase performed 1 month after TARE shows reduced arterial enhancement (red arrows). (F) An 18F-FDG PET/CT scan at the same level as (B) shows reduced metabolism (red arrows). Tg, thyroglobulin; TSH, thyroid-stimulating hormone; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase.

  • Fig. 2. (A) Whole-body scan performed 3 days after 131I therapy. Red arrows indicate radioactive iodine (RAI)-avid masses in the neck. (B, C, D, E) RAI-avid masses in the neck (B, C, D) and RAI-refractory masses in the right acetabulum (E). The left panels show 131I single-photon emission computed tomography/computed tomography (SPECT/CT) scans, and the right panels show 18F-fluorodeoxyglucose (18F-FDG) PET/CT scans at the same level. (F) A RAI-refractory mass in the liver. (G) A dynamic CT scan 3 months after transarterial radioembolization.


Reference

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