Tuberc Respir Dis.  1988 Dec;35(4):256-261. 10.4046/trd.1988.35.4.256.

Serum Concentrations of Vitamine D Metabolites in Patients with Untreated Tuberculosis

• KMID: 2528586
• DOI: http://doi.org/10.4046/trd.1988.35.4.256

Abstract

T o evaluate the status of serum vitamin D metabolites in patients with untreated tuberculosis, the serum levels of 25-OHD₃ and 1.25-(OH)₂D₃ in 20 patients with untreated pulmonary tuberculosis and tuberculous pleurisy were compared with those in age and sex matched 20 healthy controls. The results were as follows; 1) Mean serum 25-OHD₃ concentrations in tubercul osis and control group were 14.6±7.5 ng/ ml and 15.0±5.0 ng/ ml respectively, and there was no significant difference (P > 1.0). 2) Mean serum 1.25-(OH)₂D₃ concentrations in tubercul osis a nd control group were 28.5±9.8 pg/ ml and 30.2±10.3 pg/ ml respectively, a nd there was no significant di fference (P > 1.0). 3) Mean serum 25-OHD₃ concentration in patients with tuberculous pleurisy was significantly lower than that in control subjects (P < 0.05). This study suggested that there was no significant association between tuberculosis and serum vitamin D metabolites in Korean patients, but vitamin D might be associated with tuberculous pleurisy.