Genomics Inform.  2022 Mar;20(1):e10. 10.5808/gi.21083.

Publication trends of somatic mutation and recombination tests research: a bibliometric analysis (1984‒2020)

Affiliations
  • 1Department of Biology, Faculty of Sciences, Akdeniz University, 07058 Campus, Antalya, Turkey

Abstract

Human exposure to pollutants has been on the rise. Thus, researchers have been focused on understanding the effect of these compounds on human health, especially on the genetic information by using various tests, among them the somatic mutation and recombination tests (SMARTs). It is a sensitive and accurate method applicable to genotoxicity analysis. Here, a comprehensive bibliometric analysis of SMART assays in genotoxicity studies was performed to assess publication trends of this field. Data were extracted from the Web of Science database and analyzed by the bibliometric tools HistCite, Biblioshiny (RStudio), VOSViewer, and CiteSpace. Results have shown an increase in the last 10 years in terms of publication. A total of 392 records were published in 96 sources mainly from Brazil, Spain, and Turkey. Research collaboration networks between countries and authors were performed. Based on document co-citation, five large research clusters were identified and analyzed. The youngest research frontier emphasized on nanoparticles. With this study, how research trends evolve over years was demonstrated. Thus, international collaboration could be enhanced, and a promising field could be developed.

Keyword

bibliometric; cancer; genotoxicity; SMART; Web of Science
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