Acute Crit Care.  2022 Feb;37(1):127-130. 10.4266/acc.2021.01263.

Inhaled iloprost can improve oxygenation and shunt fraction in severe COVID-19

• Serbanescu-Kele Apor de Zalán
• Foudraine NA
• Le Noble JL

• KMID: 2527917
• DOI: http://doi.org/10.4266/acc.2021.01263

Figure

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  Figure 1. (A) The left panel depicts absolute changes in oxygenation index (OI), and the right panel shows relative changes in OI after iloprost administration in eight patients with severe coronavirus disease 2019 (COVID-19). A similar figure, including all measurements obtained, is presented in Supplementary Figure 1A. (B) The left panel depicts absolute changes and the right panel shows relative changes in shunt fraction (Qs/Qt) after iloprost administration in eight patients with severe COVID-19. A similar figure that includes all measurements obtained is shown in Supplementary Figure 1B. (A, B) Only measurements obtained around the first dose of iloprost received by each patient were included. The X axis shows the timepoints at which measurements were performed.

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  Figure 2. he relationship between changes in oxygenation index (OI) and shunt fraction (Qs/Qt) after iloprost administration in 11 measurements obtained in eight patients with severe coronavirus disease 2019 (COVID-19). X-axis and Y-axis include the first available measurement after administration of iloprost, expressed relative to the values obtained at baseline (which were set to 1.0).

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