J Vet Sci.  2022 Mar;23(2):e30. 10.4142/jvs.21219.

Muscular and collagenous cerebellar choristoma in a dog

Affiliations
  • 1Programa de Pós Graduação em Medicina Veterinária, Universidade Federal de Santa Maria (UFSM), 97105-900 Santa Maria, RS, Brazil
  • 2Departamento de Morfologia, Laboratório de Patologia Veterinária, Universidade Federal de Santa Maria (UFSM), 97105-900 Santa Maria, RS, Brazil
  • 3Departamento de Clínica de Pequenos Animais, Universidade Federal de Santa Maria (UFSM), 97105-900 Santa Maria, RS, Brazil

Abstract

This report aims to describe the first case of muscular and collagenous choristoma in a dog. A 10-yr-old female mixed-breed dog presented with lateral recumbence, vocalization, positional vertical nystagmus, divergent strabismus, anisocoria, and status epilepticus. The clinical condition evolved to stupor and ultimately, death. Necropsy revealed a white mass causing an irregular increase in the volume of the cerebellar vermis. In histological analysis, a well circumscribed, unencapsulated mass was observed in the cerebellum, consisting of fibers of striated skeletal muscle and collagen fibers, mostly mineralized. Based on the histopathological and histochemical findings, a diagnosis of muscular and collagenous cerebellar choristoma was made.

Keyword

Choristoma; cerebellum; dog; neuropathology; immunohistochemistry
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