J Pathol Transl Med.  2022 Mar;56(2):111-112. 10.4132/jptm.2022.01.21.

Renal cell carcinoma concomitant with multiple myeloma

Affiliations
  • 1Department of Pathology, All India Institute of Medical Sciences, New Delhi, India
  • 2Department of Medical Oncology, All India Institute of Medical Sciences, New Delhi, India


Figure

  • Fig. 1. (A) Microphotograph of lytic lesion biopsy shows sheets of mature plasma cells with mild atypia. (B) Cells are immunopositive for CD138, (C) while negative for cytokeratin. (D) Biopsy of the renal mass shows cells arranged in sheets with clear cytoplasm and small nuclei. The cells are immunopositive for cytokeratin (E) and CD10 (F).


Reference

References

1. Ojha RP, Evans EL, Felini MJ, et al. The association between renal cell carcinoma and multiple myeloma: insights from population-based data. BJU Int. 2011; 108:825–30.
Article
2. Shields LB, Kalebasty AR. Concurrent renal cell carcinoma and hematologic malignancies: Nine case reports. World J Clin Oncol. 2020; 11:644–54.
Article
3. Li N, Liu X, Song Y, et al. The synchronous presence of multiple myelomas and other primary malignant tumors: case series with literature review. Cancer Manag Res. 2020; 12:2829–38.
4. Sakai A, Kawano M, Kuramoto A. Interleukin-6 produced by renalcell carcinoma cells and progression of multiple myeloma. N Engl J Med. 1991; 324:1893–4.
Article
5. Choueiri TK, Baz RC, McFadden CM, et al. An association between renal cell carcinoma and multiple myeloma: a case series and clinical implications. BJU Int. 2008; 101:712–5.
Article
6. Padhi S, Sahoo PK, Banerjee D, et al. Renal cell carcinoma and plasma cell myeloma: unique association and clinical implications. Urol Ann. 2014; 6:252–6.
Article
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