J Breast Cancer.
2021 Dec;24(6):554-560. 10.4048/jbc.2021.24.e47.
Imaging Protocol and Criteria for Evaluation of Axillary Lymph Nodes in the NAUTILUS Trial
- Affiliations
-
- 1Department of Radiology, Seoul National University Hospital, Seoul, Korea
- 2Department of Radiology and Research Institute of Radiology, Asan Medical Center, Seoul, Korea
- 3Department of Radiology and Center for Imaging Science, Samsung Medical Center, Seoul, Korea
- 4Department of Radiology, Seoul National University Bundang Hospital, Seoul, Korea
- 5Department of Radiology, National Cancer Center, Goyang, Korea
- 6Department of Radiology, Research Institute of Radiological Science, Severance Hospital, Seoul, Korea
- 7Department of Radiology, Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, Seoul, Korea
- 8Department of Radiology, Ajou University Medical Center, Suwon, Korea
- KMID: 2524797
- DOI: http://doi.org/10.4048/jbc.2021.24.e47
Abstract
- Axillary ultrasonography (US) is the most commonly used imaging modality for nodal evaluation in patients with breast cancer. No Axillary Surgical Treatment in Clinically Lymph Node-Negative Patients after Ultrasonography (NAUTILUS) is a prospective, multicenter, randomized controlled trial investigating whether sentinel lymph node biopsy (SLNB) can be safely omitted in patients with clinically and sonographically node-negative T1–2 breast cancer treated with breast-conserving therapy. In this trial, a standardized imaging protocol and criteria were established for the evaluation of axillary lymph nodes. Women lacking palpable lymph nodes underwent axillary US to dismiss suspicious nodal involvement. Patients with a round hypoechoic node with effaced hilum or indistinct margins were excluded. Patients with T1 tumors and a single node with a cortical thickness ≥ 3 mm underwent US-guided biopsy. Finally, patients with negative axillary US findings were included. The NAUTILUS axillary US nodal assessment criteria facilitate the proper selection of candidates who can omit SLNB.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Ectopic Schistosomiasis Involving Axillary Lymph Nodes
- Differential Diagnosis of Axillary Inflammatory and Metastatic Lymph Nodes in Rabbit Models by Using Diffusion-Weighted Imaging: Compared with Conventional Magnetic Resonance Imaging
- Ultrasonography for Staging Axillary Lymph Node in Breast Cancer Patients
- Efficacy of Ultrasound-Guided Core Needle Biopsy in Detecting Metastatic Axillary Lymph Nodes in Breast Cancer
- Axillary Lymph Node Sarcoidosis
