Korean J Pain.  2022 Jan;35(1):106-113. 10.3344/kjp.2022.35.1.106.

Comparison of treatment outcomes in chronic coccygodynia patients treated with ganglion impar blockade versus caudal epidural steroid injection: a prospective randomized comparison study

Affiliations
  • 1Division of Pain Medicine, Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Marmara University, Istanbul, Turkey
  • 2Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Marmara University, Istanbul, Turkey
  • 3Pain Clinic, Adıyaman Education and Research Hospital, Adıyaman, Turkey

Abstract

Background
Coccygodynia is one of the chronic, refractory painful musculoskeletal disorders. Interventional procedures are applied to patients unresponsive to initial treatment in coccygodynia. This study aims to compare the treatment outcomes of ganglion impar block (GIB) and caudal epidural steroid injection (CESI) in patients with chronic coccygodynia.
Methods
This study was a prospective randomized comparison study conducted between June 2019 and January 2021. Patients diagnosed with chronic coccygodynia were randomly divided into two groups: the GIB group and the CESI group. The severity of pain, presence of neuropathic pain, and quality of life were evaluated using the Numeric Rating Scale, Leeds Assessment of the Neuropathic Symptoms and Signs Scale, and Short Form-12 Health Survey (SF-12), respectively.
Results
A total of 34 patients in each group were included in the final analyses. While there was a significant decrease in pain intensity in both groups in the 3-month follow-up, this decrease was more significant in the GIB group at the 3rd week. There was a significant improvement in the SF-12 physical score and the number of patients with neuropathic pain in both groups in the 3rd week, but this improvement was not observed in the 3rd month.
Conclusions
Although GIB may provide more pain relief in short term, both GIB and CESI are useful treatment methods in coccygodynia unresponsive to more conservative treatments.

Keyword

Chronic Pain; Coccyx; Ganglia; Sympathetic; Injections; Epidural; Musculoskeletal Pain; Neuralgia; Pain Measurement; Pelvic Girdle Pain; Quality of Life; Steroids; Treatment Outcome

Figure

  • Fig. 1 (A) Image of an “inverse comma” sign at ganglion impar block. (B) Spread of the mixture in the caudal epidural space at caudal epidural steroid injection.

  • Fig. 2 Flow diagram.

  • Fig. 3 Change in main outcome measures in follow-up periods (mean scores were given for NRS and SF-12, while numbers of patients with neuropathic pain were shown for LANSS). CESI: caudal epidural steroid injection, GIB: ganglion impar block, NRS: numeric rating scale, LANSS: Leeds Assessment of Neuropathic Symptoms and Signs Scale, SF-12: Short Form-12 Health Survey.


Cited by  1 articles

Coccydynia: anatomic origin and considerations regarding the effectiveness of injections for pain management
Shin-Hyo Lee, Miyoung Yang, Hyung-Sun Won, Yeon-Dong Kim
Korean J Pain. 2023;36(3):272-280.    doi: 10.3344/kjp.23175.


Reference

1. Garg B, Ahuja K. 2021; Coccydynia-a comprehensive review on etiology, radiological features and management options. J Clin Orthop Trauma. 12:123–9. DOI: 10.1016/j.jcot.2020.09.025. PMID: 33716437. PMCID: PMC7920198.
Article
2. Patijn J, Janssen M, Hayek S, Mekhail N, Van Zundert J, van Kleef M. 2010; 14. Coccygodynia. Pain Pract. 10:554–9. DOI: 10.1111/j.1533-2500.2010.00404.x. PMID: 20825565.
3. Lirette LS, Chaiban G, Tolba R, Eissa H. 2014; Coccydynia: an overview of the anatomy, etiology, and treatment of coccyx pain. Ochsner J. 14:84–7. PMID: 24688338. PMCID: PMC3963058.
4. Karadimas EJ, Trypsiannis G, Giannoudis PV. 2011; Surgical treatment of coccygodynia: an analytic review of the literature. Eur Spine J. 20:698–705. DOI: 10.1007/s00586-010-1617-1. PMID: 21046173. PMCID: PMC3082682.
Article
5. Foye PM. 2017; Coccydynia: tailbone pain. Phys Med Rehabil Clin N Am. 28:539–49. DOI: 10.1016/j.pmr.2017.03.006. PMID: 28676363.
6. Gunduz OH, Sencan S, Kenis-Coskun O. 2015; Pain relief due to transsacrococcygeal ganglion impar block in chronic coccygodynia: a pilot study. Pain Med. 16:1278–81. DOI: 10.1111/pme.12752. PMID: 25801345.
Article
7. Gonnade N, Mehta N, Khera PS, Kumar D, Rajagopal R, Sharma PK. 2017; Ganglion impar block in patients with chronic coccydynia. Indian J Radiol Imaging. 27:324–8. DOI: 10.4103/ijri.IJRI_294_16. PMID: 29089683. PMCID: PMC5644328.
Article
8. Sencan S, Kenis-Coskun O, Demir FGU, Cuce I, Ercalık T, Gunduz OH. 2018; Ganglion Impar block improves neuropathic pain in coccygodynia: a preliminary report. Neurol Neurochir Pol. 52:612–7. DOI: 10.1016/j.pjnns.2018.08.006. PMID: 30195465.
Article
9. Elkhashab Y, Ng A. 2018; A review of current treatment options for coccygodynia. Curr Pain Headache Rep. 22:28. DOI: 10.1007/s11916-018-0683-7. PMID: 29556817.
Article
10. Govardhani Y, RamMohan G, Abhijith S, Savithri B. 2021; A comparative retrospective study of the efficacy of caudal epidural with manipulation versus ganglion impar block with manipulation in patients with coccydynia. Indian J Pain. 35:42–5. https://www.indianjpain.org/article.asp?issn=0970-5333;year=2021;volume=35;issue=1;spage=42;epage=45;aulast=Govardhani. DOI: 10.4103/ijpn.ijpn_152_20.
Article
11. Yucel A, Senocak M, Kocasoy Orhan E, Cimen A, Ertas M. 2004; Results of the Leeds assessment of neuropathic symptoms and signs pain scale in Turkey: a validation study. J Pain. 5:427–32. DOI: 10.1016/j.jpain.2004.07.001. PMID: 15501424.
Article
12. Soylu C, Kütük B. 2021; Reliability and validity of the Turkish version of SF-12 Health Survey. Turk Psikiyatri Derg. [in press] https://www.turkpsikiyatri.com/submission/MGSDosyalar/Erkenbaski/25700-erkenbaski-en-24818.pdf. DOI: 10.5080/u25700.
Article
13. Sencan S, Edipoglu IS, Ulku Demir FG, Yolcu G, Gunduz OH. 2019; Are steroids required in the treatment of ganglion impar blockade in chronic coccydynia? A prospective double-blinded clinical trial. Korean J Pain. 32:301–6. DOI: 10.3344/kjp.2019.32.4.301. PMID: 31569923. PMCID: PMC6813902.
Article
14. Oh CS, Chung IH, Ji HJ, Yoon DM. 2004; Clinical implications of topographic anatomy on the ganglion impar. Anesthesiology. 101:249–50. DOI: 10.1097/00000542-200407000-00039. PMID: 15220800.
Article
15. Sagir O, Demir HF, Ugun F, Atik B. 2020; Retrospective evaluation of pain in patients with coccydynia who underwent impar ganglion block. BMC Anesthesiol. 20:110. DOI: 10.1186/s12871-020-01034-6. PMID: 32393277. PMCID: PMC7212553.
Article
16. Sir E, Eksert S. 2019; Comparison of block and pulsed radiofrequency of the ganglion impar in coccygodynia. Turk J Med Sci. 49:1555–9. DOI: 10.3906/sag-1906-51. PMID: 31652036. PMCID: PMC7018354.
Article
17. Ghai A, Jangra P, Wadhera S, Kad N, Karwasra RK, Sahu A, et al. 2019; A prospective study to evaluate the efficacy of ultrasound-guided ganglion impar block in patients with chronic perineal pain. Saudi J Anaesth. 13:126–30. DOI: 10.4103/sja.SJA_667_18. PMID: 31007658. PMCID: PMC6448437.
18. Ferreira F, Pedro A. 2020; Ganglion impar neurolysis in the management of pelvic and perineal cancer-related pain. Case Rep Oncol. 13:29–34. DOI: 10.1159/000505181. PMID: 32110217. PMCID: PMC7036554.
Article
19. Foye PM, Buttaci CJ, Stitik TP, Yonclas PP. 2006; Successful injection for coccyx pain. Am J Phys Med Rehabil. 85:783–4. DOI: 10.1097/01.phm.0000233174.86070.63. PMID: 16924191.
Article
20. De Andrés J, Chaves S. 2003; Coccygodynia: a proposal for an algorithm for treatment. J Pain. 4:257–66. DOI: 10.1016/S1526-5900(03)00620-5. PMID: 14622695.
Article
21. Atim A, Ergin A, Bilgiç S, Deniz S, Kurt E. 2011; Pulsed radiofrequency in the treatment of coccygodynia. Agri. 23:1–6. DOI: 10.5505/agri.2011.59002. PMID: 21341145.
Article
22. Lee DW, Lai A. 2019; Sacral burst neuromodulation via caudal approach as a treatment for chronic coccydynia. Neuromodulation. 22:992–4. DOI: 10.1111/ner.12808. PMID: 30117630.
Article
23. Kaydu A, Kiliç ET, Gökçek E, Kaçar CK. 2018; Anosmia after caudal epidural steroid injection. Anesth Essays Res. 12:291–3. DOI: 10.4103/aer.AER_14_18. PMID: 29628602. PMCID: PMC5872886.
Article
24. Kaydu A, Kılıç ET, Gökçek E, Akdemir MS. 2017; Unexpected complication after caudal epidural steroid injection: hiccup. Anesth Essays Res. 11:776–7. DOI: 10.4103/aer.AER_90_17. PMID: 28928587. PMCID: PMC5594806.
Article
25. Gupta N, Garg R, Saini S, Bharti SJ, Kumar V. 2017; An unusual complication after ganglion impar block for chronic cancer pain management. AANA J. 85:424–6. PMID: 31573500.
Full Text Links
  • KJP
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr