Clin Psychopharmacol Neurosci.
2021 Nov;19(4):789-792. 10.9758/cpn.2021.19.4.789.
Acute Hepatitis Due to Agomelatine Use in Elderly Women with Depression: Case Series
- Affiliations
-
- 1Department of Psychiatry, Changhua Christian Hospital, Changhua, Taiwan
- 2School of Medicine, Chung Shan Medical University, Taichung, Taiwan
- KMID: 2522994
- DOI: http://doi.org/10.9758/cpn.2021.19.4.789
Abstract
- Although agomelatine may be associated with an increased risk of hepatotoxicity, the incidence rate of acute hepatitis seemed divergent between clinical trials and daily practice. Whether aging or gender is a risk factor in developing hepatotoxicity due to agomelatine is not clear. We present 3 older female cases with acute hepatitis occurring due to highly probable idiosyncratic drug-induced liver injury caused by agomelatine. From these cases, regular surveillance on liver function in the older women taking antidepressants would be of benefits.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Agomelatine: The Novel Antidepressant
- Agomelatine: Antidepressant with a New Mechanism of Action
- Agomelatine versus Sertraline: An Observational, Open-labeled and 12 Weeks Follow-up Study on Efficacy and Tolerability
- Prevention of Viral Hepatitis and Vaccination
- A Study on the Experience of Depression in Elderly Women Living Alone
