J Korean Soc Radiol.  2021 Nov;82(6):1606-1612. 10.3348/jksr.2020.0154.

Early Imaging Findings of Hypertrophic Osteoarthropathy Mimicking Bone Metastasis from Extrathoracic Malignancy

• Hwang JY
• Cha JG
• Yoon YS
• Moon A

• KMID: 2522948
• DOI: http://doi.org/10.3348/jksr.2020.0154

Abstract

Hypertrophic osteoarthropathy (HOA) is a syndrome characterized by digital clubbing, periosteal bone formation, and synovial effusions. Secondary HOA is associated with intrathoracic malignancy in most cases; however, in rare cases, HOA can be caused by extrathoracic conditions. We report early ultrasound, computed tomography, magnetic resonance imaging, and bone scintigraphy findings of HOA in a patient with breast cancer. Its ambiguous clinical and imaging findings that mimicked malignant conditions are particularly interesting and informative.

Keyword

Hypertrophic Osteoarthropathy; Secondary; Breast Neoplasms; Neoplasm Metastasis; Magnetic Resonance Imaging; Ultrasonography