Korean J Otorhinolaryngol-Head Neck Surg.
2021 Nov;64(11):829-833. 10.3342/kjorl-hns.2021.00143.
Kikuchi-Fujimoto Disease Masquerading as Bilateral Lymph Node Metastasis in a Patient With Papillary Thyroid Carcinoma: A Case Report and Literature Review
- Affiliations
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- 1Department of Otorhinolaryngology-Head and Neck Surgery, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea
- 2Department of Pathology, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea
- 3Department of Radiology, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea
- KMID: 2522835
- DOI: http://doi.org/10.3342/kjorl-hns.2021.00143
Abstract
- Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is common in young Asian women under the age of 30, and is usually characterized by fever, myalgia, fatigue, and cervical lymphadenopathy. Because patients with KFD often present with necrotic lesions that are also features of lymph node metastasis, ipsilateral or bilateral lymph node enlargement in head and neck cancer patients can be disguised as lymph node metastasis. We present an unusual case of KFD mimicking bilateral metastatic papillary carcinoma of the thyroid. This study emphasizes that KFD should be considered when diagnosing lymph nodes with necrotic lesions but without malignant cells in young women.
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