Diabetes Metab J.  2021 Nov;45(6):960-965. 10.4093/dmj.2020.0225.

Short-Term Effects of the Internet-Based Korea Diabetes Prevention Study: 6-Month Results of a Community-Based Randomized Controlled Trial

• Lee JH
• Lim SY
• Cha SA
• Han CJ
• Jung AR
• Kim KR
• Yoon KH
• Ko SH

• KMID: 2522735
• DOI: http://doi.org/10.4093/dmj.2020.0225

Abstract

The aims of this study were to determine the short-term effectiveness of an internet-based lifestyle modification (LSM) program in preventing the onset of type 2 diabetes mellitus (T2DM) in prediabetes patients in community settings. A total of 415 subjects who were diagnosed with prediabetes were randomly assigned to the LSM and standard management (SM) groups. After the 6-month intervention, the LSM group had a statistically significant reduction in body weight, body mass index compared to the SM group participants. In the LSM group, blood glucose levels were significantly decreased after intervention and the clinical improvement effect was evident in the group that achieved the target weight loss of 5% or more of the initial weight for 6 months. Internet-based 6-month-intensive LSM programs conducted by public health center personnel are an effective way to provide lifestyle intervention programs and encourage maintenance of healthy behaviors in subjects with a high risk of T2DM in community settings.

Keyword

Behavior therapy; Diabetes mellitus, type 2; Internet-based intervention; Life style; Prediabetic state

Figure

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  Fig. 1. Changes in clinical outcomes from baseline to 6 months in the lifestyle modification group, according to whether subjects achieved their target weight. (A) Mean changes in anthropometric measures and blood pressure, (B) mean changes in blood glucose and insulin level, (C) mean changes in lipid profiles. White bar represents the changes in clinical parameters in the unachieved the weight goal, while grey bar represents the change in clinical parameters in the achieved the weight goal group. Repeated measures analysis of covariance (ANCOVA) test was used for panels A, B, and C. We adjusted for age and sex. BMI, body mass index; HbA1c, glycosylated hemoglobin; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol. aP<0.05, bP<0.001 for the difference between two groups.

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