Pediatr Gastroenterol Hepatol Nutr.  2021 Nov;24(6):528-534. 10.5223/pghn.2021.24.6.528.

Donor Surgical Morbidity in Pediatric Living-Donor Liver Transplant: A Portuguese Experience

• Santos JPFd
• Martins R
• Lopes MF

• KMID: 2522294
• DOI: http://doi.org/10.5223/pghn.2021.24.6.528

Abstract

Purpose
Living-donor liver transplant emerged as an alternative treatment for end stage liver disease due to the lack of cadaveric organs availability that met the demand. In Portugal, pediatric living-donor liver transplant (P-LDLT) was initiated in 2001 in Portugal in order to compensate for the scarcity of cadaveric organs for such cases. The aim of this study was to retrospectively analyze the morbi-mortality of the 28 donors included in P-LDLT program performed at Coimbra's Pediatric Hospital (CHUC), a Portuguese reference center.
Methods
We retrospectively collected pertinent donor data and stratified complications according to Clavien's scoring system.
Results
In total, 28.6% (n=8) of the donors had surgical complications. According to Clavien-Dindo's classification, two donors had major complications (Clavien grade ≥3), four donors had grade 2 complications, and two donors had grade 1 complications. There were no P-LDLT-related mortalities in the present case series. The most common verified complications were biliary tract injuries and superficial incisional infections, which are consistent with the complications reported in worldwide series.
Conclusion
These patients from CHUC shows that donor hepatectomy in P-LDLT is a safe procedure, with low morbidity and without mortality.

Keyword

Liver transplantation; Living donors; Morbidity