J Korean Diet Assoc.  2021 Nov;27(4):248-262. 10.14373/JKDA.2021.27.4.248.

The Effect of Dementia Prevention Nutrition Program Using MIND Diet on the Changes in Cognitive Function of the Elderly with High-Dementia Risks

  • 1Dept. of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea
  • 2Dept. of Neurology, Inha University Hospital, Incheon 22332, Korea
  • 3Dept. of Psychiatry, Ajou University School of Medicine, Suwon 16499, Korea
  • 4Dept. of Neurology, Ewha Womans University School of Medicine, Seoul 07985, Korea
  • 5Dept. of Neurology, Ajou University School of Medicine, Suwon 16499, Korea
  • 6Dept. of Neurology, Bobath Memorial Hospital, Seongnam 13552, Korea


This study examined the effect of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet of the Korean multi-domain dementia prevention program on the cognitive functions of the elderly with dementia risk factors. We developed the program including nutrition, exercise, cognitive training, vascular disease prevention, and motivation. One- hundred and fifty-three participants aged 60∼79 years with at least 1 dementia risk factor were randomly assigned in a 1:1:1 ratio to the facility-based intervention (FMI), home-based intervention (HMI), and the control group. The nutrition education program consisted of 10 classes over 24 weeks: the FMI received 7 group sessions and three 1:1 sessions, the HMI received 4 group sessions and three 1:1 sessions with 3 homework sessions. The Nutrition Quotient for Elderly (NQ-E) and the Mini Nutritional Assessment (MNA) were used to evaluate nutritional status. The Repeatable Battery for the Assessment Neuropsychological Status (RBANS), Korean Mini-Mental State Examination (K-MMSE), and the Cognitive Complaint Interview (CCI) were used to evaluate cognitive functions. A total of 136 people completed the program with an 11.1% dropout rate. The NQ-E (P=0.009) and RBANS (P=0.001) scores significantly increased in the FMI (N=45) and HMI (N=49) groups compared to the control group (N=42) after the study. The changes in the score of MNA and CCI did not differ significantly between groups. In conclusion, the nutritional intervention which focused on the MIND diet as a part of a multi-domain intervention program had a positive effect on the improvement of healthy eating habits and cognitive function scores in the high-risk dementia group.


Mediterranean-DASH Intervention for Neurodegenerative Delay diet; dementia; Nutrition Quotient for Elderly; cognitive function
Full Text Links
  • JKDA
export Copy
  • Twitter
  • Facebook
Similar articles
Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr