Investig Clin Urol.  2021 Nov;62(6):672-680. 10.4111/icu.20210266.

Accuracy comparison study of new smartphone-based semen analyzer versus laboratory sperm quality analyzer

• Park MJ
• Lim MY
• Park HJ
• Park NC

• KMID: 2521825
• DOI: http://doi.org/10.4111/icu.20210266

Abstract

Purpose
This study aimed to test the clinical efficacy of a portable smartphone-based App assisted semen analysis (SA) system, O'VIEW-M PRO® to clinically accurate in comparison with results of laboratory-based conventional semen analyses including manual microscopic and computer-assisted semen analysis (CASA) for self-evaluation of seminal parameters.
Materials and Methods
From January to May 2021, a total of 39 semen samples were analyzed for the sperm concentration and motility with new smartphone-based App assisted semen analyzer, O'VIEW-M PRO®, and results compared with those from laboratory-based manual microscopic SA with Makler Counting Chamber and CASA.
Results
The coefficient factors among the results of the measurement with Makler chamber and laboratory-based CASA comparing to O'VIEW-M PRO^® were 0.666 and 0.655 for sperm density, 0.662 and 0.658 for sperm motility, respectively. There were no particular problems with clinical use of the O'VIEW-M PRO^®. Device performance in classifying samples is positive (<15×10⁶ sperm/ mL) and negative (>15×10⁶ sperm/mL) for sperm concentration criteria, and positive (<40%) and negative (>40%) for sperm motility criteria. The smartphone-based App assisted SA O'VIEW-M PRO^® showed a sensitivity of 92.6%, a specificity of 66.7%, and overall accuracy rate of 84.6%.
Conclusions
This study shows a novel smartphone-based App assisted SA system. O'VIEW-M PRO^® can easily obtain semen parameter information through self-diagnosis at home and induce infertile men's treatment and help patients after receiving infertile men's treatment before receiving treatment.

Keyword

Male infertility; Semen analysis; Smartphone; Sperm count