Asian Spine J.  2021 Oct;15(5):566-574. 10.31616/asj.2020.0353.

Impact of Screw Diameter and Length on Pedicle Screw Fixation Strength in Osteoporotic Vertebrae: A Finite Element Analysis

• Matsukawa K
• Yato Y
• Imabayashi H

• KMID: 2521547
• DOI: http://doi.org/10.31616/asj.2020.0353

Abstract

Study Design: Biomechanical study. Purpose: To quantitatively investigate the effect of screw size on screw fixation in osteoporotic vertebrae with finite element analysis (FEA) Overview of Literature: Osteoporosis poses a challenge in spinal instrumentation; however, the selection of screw size is directly related to fixation and is closely dependent on each surgeon’s experience and preference.
Methods
Total 1,200 nonlinear FEA with various screw diameters (4.5–7.5 mm) and lengths (30–50 mm) were performed on 25 patients (seven men and 18 women; mean age, 75.2±10.8 years) with osteoporosis. The axial pullout strength, and the vertebral fixation strength of a paired-screw construct against flexion, extension, lateral bending, and axial rotation were examined. Thereafter, we calculated the equivalent stress of the bone-screw interface during nondestructive loading. Then, using diameter parameters (screw diameter or screw fitness in the pedicle [%fill]), and length parameters (screw length or screw depth in the vertebral body [%length]), multiple regression analyses were performed in order to evaluate the factors affecting various fixations.
Results
Larger diameter and longer screws significantly increased the pullout strength and vertebral fixation strength; further, they decreased the equivalent stress around the screws. Multiple regression analyses showed that the actual screw diameter and %length were factors that had a stronger effect on the fixation strength than %fill and the actual screw length. Screw diameter had a greater effect on the resistance to screw pullout and flexion and extension loading (β =0.38–0.43, p <0.01); while the %length had a greater effect on resistance to lateral bending and axial rotation loading (β =0.25–0.36, p <0.01) as well as mechanical stress of the bone-screw interface (β =−0.42, p <0.01).
Conclusions
The screw size should be determined based on the biomechanical behavior of the screws, type of mechanical force applied on the corresponding vertebra, and anatomical limitations.

Keyword

Finite element analysis; Pedicle screws; Osteoporosis; Screw size; Fixation strength