Korean J Med.  2021 Apr;96(2):85-91. 10.3904/kjm.2021.96.2.85.

Anti-Diabetic Drugs in Cardiovascular Disease

• Kim SE
• Yoo BS

• KMID: 2521218
• DOI: http://doi.org/10.3904/kjm.2021.96.2.85

Abstract

Diabetes is one of the important risk factors in cardiovascular disease associated with atherosclerosis, and cardiovascular disease is the leading cause of death in patients with diabetes mellitus. Recent randomized placebo-controlled cardiovascular outcome trials of all new antidiabetic drugs have linked SGLT-2 inhibitors and GLP1-agonists to not only increased cardiovascular stability but significant reduction of cardiovascular disease. These results have led to preferential selection of the most effective and beneficial antidiabetic drugs with the evidence of cardiovascular safety and efficacy. Herein, we address cardiovascular stability and the effectiveness of antidiabetic drugs, focusing on recently developed ones.

Keyword

Anti-diabetic drugs; Safety; Cardiovascular outcomes trials