J Chest Surg.  2021 Oct;54(5):416-418. 10.5090/jcs.20.133.

Unilateral Giant Bullae: Pulmonary Placental Transmogrification Should Be Kept in Mind: Case Reports

• M. Hamad AM
• M. Nosseir M
• M. Alorainy S

• KMID: 2521126
• DOI: http://doi.org/10.5090/jcs.20.133

Abstract

Placental transmogrification is a peculiar clinical entity of the lung of uncertain etiology. We report 2 cases of pulmonary placental transmogrification in 2 patients of different nationalities. Both of them had no history of smoking or chronic lung disease. The main presentations were dyspnea and chest pain. Radiologic studies showed a unilateral giant bulla in both patients; additional pneumothorax was present in only 1patient. They underwent surgical bullectomy. Histopathologic studies revealed the presence of intracystic placenta-like villous structures and a diagnosis of placental transmogrification was made. Placental transmogrification should be considered in cases of unilateral bullae.

Keyword

Emphysema; Bullae; Placenta; Case report