J Pathol Transl Med.  2021 Sep;55(5):366-367. 10.4132/jptm.2021.07.28.

What’s new in gynecologic pathology 2021: ovary and fallopian tube

• Turashvili G
• Lastra R

• KMID: 2520177
• DOI: http://doi.org/10.4132/jptm.2021.07.28

Abstract

The 5th edition of the World Health Organization (WHO) Classification of Female Genital Tumors was published in 2020. Although the classification of ovarian and fallopian tube neoplasms is largely unchanged from the prior (4th) edition, this newsletter compiles the most important refinements in these organ sites, including serous and non-serous epithelial tumors, and sex cord-stromal tumors.

Figure

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  Fig. 1. Endometrioid adenocarcinoma with mucinous differentiation.

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  Fig. 2. Dedifferentiated carcinoma composed of undifferentiated carcinoma and low-grade endometrioid adenocarcinoma.

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  Fig. 3. Mixed carcinoma composed of clear cell carcinoma and endometrioid adenocarcinoma.

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  Fig. 4. Moderately differentiated Sertoli-Leydig cell tumor with heterologous elements (intestinal-type glands) and somatic DICER1 mutation.

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  Fig. 5. Gynandroblastoma composed of Sertoli-Leydig cell tumor and adult-type granulosa cell tumor.